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_aAIKTC-KRRC _cAIKTC-KRRC |
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_aSharma, Dhruva Kumar _927747 |
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_aStudy of acute transfusion reactions in a teaching hospital of Sikkim _b:a hemovigilance initiative |
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| 250 | _aVol.47(4), Jul-Aug | ||
| 260 |
_aMumbai _bWolter Kluwer _c2015 |
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| 300 | _a370-374p. | ||
| 520 | _aBlood transfusions are inherently associated with risks ranging in severity from minor to life-threatening. Continuous monitoring of transfusion related complications can promote understanding of factors contributing to transfusion reactions and help to formulate necessary remedial measures. This study was designed to analyze the frequency and nature of transfusion reactions reported to the blood bank of a remote North East Indian teaching hospital. Materials and Methods: All acute transfusion reactions (ATRs) reported to the blood bank over a period of 20 months (May 2013 to January 2015) were reviewed and analyzed. The risk of transfusion reactions associated with each individual component was assessed. Results: A total of 3455 units of whole blood and component transfusions were carried out of which a total of 32 (0.92%) ATRs were encountered. Packed red blood cells (PRBCs) (n = 15, P = 0.06) and whole blood (WB) (n = 13, P = 0.83) were most commonly implicated. Allergic reaction was the most frequent transfusion reaction encountered (65.6%), seen most commonly with PRBC (risk of 0.76%, P = 0.42), and WB (risk of 0.68%, P = 0.63) transfusions. This was followed by febrile reactions (28.1%), which were seen more commonly with PRBCs (risk of 0.57%, P = 0.016). No reactions were observed with platelet transfusions. | ||
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_aPHARMACOLOGY _94774 |
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_aDatta, Supratim _927748 |
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| 773 | 0 |
_dAndheri - Mumbai Wolters Kluwer India Private Limited _tIndian Journal of Pharmacology _x0253-7613 |
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| 856 |
_uhttps://journals.lww.com/iphr/fulltext/2015/47040/study_of_acute_transfusion_reactions_in_a_teaching.6.aspx _yClick here |
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