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040			_aAIKTC-KRRC _cAIKTC-KRRC
100			_aKhan, Neelofar _927753
245			_aImmunoprophylactic potential of wheat grass extract on benzene-induced leukemia _b: an in vivo study on murine model
250			_aVol.47(4), Jul-Aug
260			_aMumbai _bWolter Kluwer _c2015
300			_a394-397p.
520			_aWheat grass (Triticum aestivum) is a gift of nature given to mankind. A number of scientific research on wheatgrass establishes its anticancer and antioxidant potential. Current work was focused to determine antileukemic effect of wheat grass. Materials and Methods: The commercial wheatgrass powder was extracted with 95% of methanol. Methanol extract of wheat grass was studied for acute oral toxicity as per revised Organization for Economic Cooperation and Development Guidelines number 423. Leukemia was successfully induced in Wister rats by intravenous injection of benzene. The blood was collected and analyzed for hematological parameters. Phagocytotic activity of the extract was determined. Results: Phytochemical screening revealed the presence of flavonoids, phenolics, carbohydrates, and amino acids. From acute toxicity studies, it was found that the methanol extract of wheatgrass was safe up to a dose level of 2000 mg/kg of body weight. Outcomes of hematological parameters in various experimental groups of murine model demonstrated antileukemic effect of extract. Methanol extract of wheatgrass aroused the process of phagocytosis of killed Candida albicans and also demonstrated a significant chemotactic activity at all tested concentrations.
650		0	_aPHARMACOLOGY _94774
700			_aGaneshpurkar, Aditya _927651
773	0		_x0253-7613 _tIndian Journal of Pharmacology _dAndheri - Mumbai Wolters Kluwer India Private Limited
856			_uhttps://journals.lww.com/iphr/fulltext/2015/47040/immunoprophylactic_potential_of_wheat_grass.10.aspx _yClick here
942			_2ddc _cAR
999			_c23782 _d23782