000			01929 a2200217 4500
003			OSt
005			20251212105520.0
008			251212b |||||||| |||| 00| 0 eng d
040			_aAIKTC-KRRC _cAIKTC-KRRC
100			_aPatil, Rupali Arun _927754
245			_aAnti-hyperbilirubinemic and wound healing activity of aqueous extract of Calotropis procera leaves in Wistar rats
250			_aVol.47(4), Jul-Aug
260			_aMumbai _bWolter Kluwer _c2015
300			_a398-402p.
520			_aThe aim of this study was to evaluate the bilirubin lowering and wound healing property of aqueous extract of Calotropis procera (AECP) leaves in Wistar rats. Materials and Methods: Albino Wistar rats of either sex were used for the study. Bilirubin lowering property of C. procera leaves was evaluated using phenylhydrazine and paracetamol as inducing agents followed by measuring the concentration of serum total bilirubin in hyperbilirubinemic rats. Wound healing property was evaluated using incision and excision models by measuring tensile breaking strength, percentage wound contractions, and epithelization days, respectively. Statistical Analysis: Statistical comparison between groups in each experiment was done with one-way analysis of variance followed by Dunnett's test. Results: AECP showed a significant (P < 0.05) decrease in concentrations of serum total bilirubin in hyperbilirubinemic rats as well as significant (P < 0.05) increase in breaking strength and percentage wound contractions with decreased epithelization period when compared to control groups.
650		0	_aPHARMACOLOGY _94774
700			_aMakwana, Aakash B. _927755
773	0		_x0253-7613 _tIndian Journal of Pharmacology _dAndheri - Mumbai Wolters Kluwer India Private Limited
856			_uhttps://journals.lww.com/iphr/fulltext/2015/47040/anti_hyperbilirubinemic_and_wound_healing_activity.11.aspx _yClick here
942			_2ddc _cAR
999			_c23783 _d23783