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040 _aAIKTC-KRRC
_cAIKTC-KRRC
100 _99674
_aIsah, Abdulmuminu
245 _aGenotype and abo blood group association with prevalence of malaria among patients in university of nigeria medical center: a cross-sectional evaluation
250 _aVol. 11 (06)
260 _aBhopal
_bInnovare Academic Sciences Pvt Ltd
_c2019
300 _a28-32p.
520 _aThe aim of this study was to evaluate the prevalence of malaria and its relationship with the ABO blood group and genotype at the University of Nigeria Medical Centre. Methods: The study had a prospective cross-sectional design in which malaria status and blood groups and genotype were determined. All collected data were analysed using Statistical product and services Solution (V.21). Frequencies and percentages were used to describe the data while Chi-square and Pearson correlation were used to determine associations between malaria prevalence and patients’ demographic and clinical characteristics. Statistical significance was considered for p<0.05. Results: Three hundred and twenty-three (323) patients were tested for malaria, 245(75.9%) of whom tested positive. The prevalence was highest for patient’s aged 19-25 y (28.5%). The difference was statistically significant for age: χ2 (5) = 33.60, p = 0.0005. There were more blood group O (57.6%) among the patients, while AA genotype was the majority (72.4%). Those with blood group O had the highest prevalence of malaria (33.7%) and it was statistically significant (χ2 (3) = 72.10, p = 0.0005)). Correlation showed that the association between blood group and malaria prevalence was moderate (R = 0.457). The AA genotype had more incidence of malaria (54.5%), but the difference was not statistically significant. Conclusion: The prevalence of malaria was high among the patients surveyed. Its association with the patients’ ABO blood group was established to be statistically significant, with blood group O having the highest incidence. Although AA genotype was observed to have the highest cases of malaria, the relationship was found not to be significant.
650 0 _94639
_aPHARMACEUTICS
700 _99676
_aAnosike, Chibueze
773 0 _dBhopal Innovare Academic Sciences Pvt Ltd
_tInternational journal of pharmacy and pharmaceutical science
_x0975 – 1491
856 _uhttps://innovareacademics.in/journals/index.php/ijpps/article/view/30218
_yClick here
942 _2ddc
_cAR