000			a
999			_c9820 _d9820
003			OSt
005			20191023091559.0
008			191023b xxu||||| |||| 00| 0 eng d
040			_aAIKTC-KRRC _cAIKTC-KRRC
100			_99993 _aMisir, Sema
245			_aRelease of Doxorubicin’s Active Ingredient from the Hydrogels Derived from Acrylamide and their Biological Functions
250			_aVol.53(1), Jan-Mar
260			_aBengaluru _bIndian journal of pharmaceutical education and research _c2019
300			_a171-177p.
520			_aPoly (HEMA/acrylamide/ methyl methacrylate) (PHAM) and Poly (Acrylamide/ methyl methacrylate)(PAM) polymers were synthesized for using in the release of Doxorubicin drug. Poly (HEMA/acrylamide/methyl methacrylate) (PHAM) and Poly (Acrylamide/methyl methacrylate) (PAM) composite hydrogels were prepared by a radical addition reaction in aqueous media formed by HEMA, acrylamide, and methacrylamide, with the presence of N,N’-methylenebisacrylamide. The characterization of the polymer was performed by FTIR analysis. Swelling and drug absorption properties of the polymers were analyzed in distilled water. Polymers’ toxic effects were investigated by XTT assay. It has been observed that the entire drug, which was added to the solution with 1 g of polymer, was absorbed for 3.5 h. The absorption of these polymers was found quite high. PHAM polymer showed >800% swelling and PAM polymer showed >600% at 600 min. PHAM polymer was less toxic than PAM polymer. These results, this new polymer is very suitable for the release of Doxorubicin drug
650		0	_94639 _aPHARMACEUTICS
700			_910053 _aHepoukar, Ceylan
773	0		_dBengluru Association of Pharmaceutical Teachers of India (APTI) _x0019-5464 _tIndian journal of pharmaceutical education and research
856			_uhttps://www.ijper.org/sites/default/files/IndJPhaEdRes_53_1_171.pdf _yClick here
942			_2ddc _cAR