Tahir, M. F.
Evaluation of crude and modified cordia myxa gum for its nutraceutical benefits - Vol.83(4), July-Aug - Mumbai Indian Journal of Pharmaceutical Science 2021 - 671-678p.
Plants are a rich source of safe and valuable bioactive compounds and since ancient times they have been
used as medicines. Medicinal herbs are used as traditional means of treating many human diseases in many
parts of the world. In current study, the green synthesis pathway was investigated for modification, reducing
and crown potential of Cordia myxa gum for the synthesis of silver nanoparticles. The seeding process
and the synthesis of silver nanoparticles were tracked by taking ultraviolet/visible absorption spectra
during the reaction. Nutritional as well as medicinal potential of raw and modified gums were analyzed.
Synthesized spherical nanoparticles were up to 65 nm in size. The ultraviolet/visible spectroscopic results
revealed an intense peak at 428 nm together with other small peaks in the region of 390-450 nm due to the
presence of nanoparticles of polydispersed silver. The purified gum showed the highest phenolic contents
(i.e. 14.71±0.04 mg) and percentage scavenging activity (i.e. 87.92±2.25). The maximum bactericidal
activity was showed by nanoformulated gum against Escherichia coli with inhibition zone of 42 mm while
minimum was found to be against Staphylococcus aureus with inhibition zone of 14 mm. Nano formulated
gum samples also exhibited optimal fungicidal effects against Fusarium solani with inhibition zone of
11.09 mm and Aspergillus niger with inhibition zone of 15.53 mm. The results of current study portrayed
that modifications in Cordia myxa gum would be beneficial to food products as an additive.
PHARMACEUTICS
Evaluation of crude and modified cordia myxa gum for its nutraceutical benefits - Vol.83(4), July-Aug - Mumbai Indian Journal of Pharmaceutical Science 2021 - 671-678p.
Plants are a rich source of safe and valuable bioactive compounds and since ancient times they have been
used as medicines. Medicinal herbs are used as traditional means of treating many human diseases in many
parts of the world. In current study, the green synthesis pathway was investigated for modification, reducing
and crown potential of Cordia myxa gum for the synthesis of silver nanoparticles. The seeding process
and the synthesis of silver nanoparticles were tracked by taking ultraviolet/visible absorption spectra
during the reaction. Nutritional as well as medicinal potential of raw and modified gums were analyzed.
Synthesized spherical nanoparticles were up to 65 nm in size. The ultraviolet/visible spectroscopic results
revealed an intense peak at 428 nm together with other small peaks in the region of 390-450 nm due to the
presence of nanoparticles of polydispersed silver. The purified gum showed the highest phenolic contents
(i.e. 14.71±0.04 mg) and percentage scavenging activity (i.e. 87.92±2.25). The maximum bactericidal
activity was showed by nanoformulated gum against Escherichia coli with inhibition zone of 42 mm while
minimum was found to be against Staphylococcus aureus with inhibition zone of 14 mm. Nano formulated
gum samples also exhibited optimal fungicidal effects against Fusarium solani with inhibition zone of
11.09 mm and Aspergillus niger with inhibition zone of 15.53 mm. The results of current study portrayed
that modifications in Cordia myxa gum would be beneficial to food products as an additive.
PHARMACEUTICS