In vivo Immunomodulatory Potential of Aqueous Extract of Different Parts of Terminalia catappa L. (Record no. 15751)

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005 - DATE AND TIME OF LATEST TRANSACTION
control field 20211224121339.0
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040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
100 ## - MAIN ENTRY--PERSONAL NAME
9 (RLIN) 15077
Author VENKATALAKSHMI, P.
245 ## - TITLE STATEMENT
Title In vivo Immunomodulatory Potential of Aqueous Extract of Different Parts of Terminalia catappa L.
250 ## - EDITION STATEMENT
Volume, Issue number Vol.83(3), May-June
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mumbai
Name of publisher, distributor, etc. Indian Journal of Pharmaceutical Science
Year 2021
300 ## - PHYSICAL DESCRIPTION
Pagination 584-593p.
520 ## - SUMMARY, ETC.
Summary, etc. Modulation of immunity is the most sought therapeutic effect as many human ailments arise because of
imbalance in immune mechanisms. In the current corona virus disease scenarios also, the role of immunity
to combat the dreadful virus has been well emphasized. Hence the present study aims at evaluating the
immunomodulatory potential of aqueous extract obtained from the different parts such as bark, fruit and
wood of Terminalia catappa. Based on the results obtained in acute oral toxicity and dose fixation studies,
medium dose (250 mg/kg body weight) of selected plant extracts were administered for 14 d to swiss albino
mice to evaluate nonspecific (neutrophil adhesion, phagocytic index) and specific (hemagglutination
antibody titer, delayed type hypersensitivity) immunomodulatory properties. The results obtained for
plant extract treated groups were compared with cyclophosphamide (immunosuppressant) treated and
levamisole (immunostimulant) treated mice. From the data of the results obtained it could be concluded
that selected parts ofTerminalia catappa have immune stimulatory as well as anti-inflammatory properties,
thereby proving their efficacy as true immunomodulators. Among the parts selected, fruits exhibited
significant immunomodulatory potential followed by bark and wood.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 4639
Topical term or geographic name entry element PHARMACEUTICS
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 15078
Co-Author BRINDHA, P.
773 0# - HOST ITEM ENTRY
Title Indian journal of pharmaceutical sciences
Place, publisher, and date of publication New Delhi
856 ## - ELECTRONIC LOCATION AND ACCESS
URL https://www.ijpsonline.com/articles/emin-vivoem-immunomodulatory-potential-of-aqueous-extract-of-different-parts-of-emterminalia-catappaem-l.pdf
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          School of Pharmacy School of Pharmacy Archieval Section 2021-12-24 2021-2022571 2021-12-24 2021-12-24 Articles Abstract Database
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