Comparison of pregabalin and nortriptyline on sleep, quality of life in postherpetic neuralgia: a prospective, randomised, open-label, parallel study (Record no. 15831)

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fixed length control field a
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control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20211230112613.0
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fixed length control field 211230b xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
100 ## - MAIN ENTRY--PERSONAL NAME
9 (RLIN) 15226
Author Khajuria, Kanika
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Title Comparison of pregabalin and nortriptyline on sleep, quality of life in postherpetic neuralgia: a prospective, randomised, open-label, parallel study
250 ## - EDITION STATEMENT
Volume, Issue number Vol.13(6)
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. M P
Name of publisher, distributor, etc. Innovare Academic Sciences Pvt Ltd
Year 2021
300 ## - PHYSICAL DESCRIPTION
Pagination 27-30p.
520 ## - SUMMARY, ETC.
Summary, etc. Objective:Aim of the present study was to compare the effectsof pregabalinand nortriptyline onsleep and qualityof life in patients of postherpetic neuralgia (PHN).Methods: The present study was conducted in48patients of PHN attending the outpatient department (OPD)of Dermatology, Government Medical College Jammu. Based oninclusion/exclusion criteria patients were randomized into two treatment groups.One group received pregabalin 150 mg/day and the other group was treated with nortriptyline25 mg/day. The patientswere followed upto eightweeks and assessed for Sleep (Medical Outcomes Study sleep scale)and quality of life (Euro QOL-5D-5L score). Clinicians Global Impression of Change (CGIC)scoreand Patient Global Impression of Change(PGIC)score were used toevaluate overall clinical improvement.Results:Both drugs significantly improved all parametersstudied (p<0.0001).On comparison,both drugs had similar effectson sleep and quality of life.However, pregabalinwas found to be better than nortriptyline at eight weeksonCGIC (p<0.004) and PGIC (p<0.0003)scores.Conclusion:Both pregabalin and nortriptyline wereequallyeffectivein improving sleep and quality of life.Overall clinical improvement was better with pregabalin than nortriptyline at eight weeks
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 4639
Topical term or geographic name entry element PHARMACEUTICS
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9 (RLIN) 15227
Co-Author Gupta, Seema
773 0# - HOST ITEM ENTRY
International Standard Serial Number 2656-0097
Title International journal of pharmacy and pharmaceutical science
Place, publisher, and date of publication Bhopal Innovare Academic Sciences Pvt Ltd
856 ## - ELECTRONIC LOCATION AND ACCESS
URL https://innovareacademics.in/journals/index.php/ijpps/article/view/41244/24891
Link text Click here
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Koha item type Articles Abstract Database
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Permanent Location Current Location Shelving location Date acquired Barcode Date last seen Price effective from Koha item type
          School of Pharmacy School of Pharmacy Archieval Section 2021-12-30 2021-2022648 2021-12-30 2021-12-30 Articles Abstract Database
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