| 000 -LEADER |
|---|
| fixed length control field |
a |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20220201155448.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
220201b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
AIKTC-KRRC |
| Transcribing agency |
AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
15735 |
| Author |
Marri, Srinivas |
| 245 ## - TITLE STATEMENT |
|---|
| Title |
Synthesis and pharmacological evaluation of 3-(3,5-dimethylisoxazol-4-yl)-2-arylthiazolidin-4-ones as potential antioxidant, anti-inflammatory and analgesic agents |
| 250 ## - EDITION STATEMENT |
|---|
| Volume, Issue number |
Vol.58(B), Jan. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
New Delhi |
| Name of publisher, distributor, etc. |
CSIR |
| Year |
2019 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Pagination |
109-119p. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
3-(3,5-Dimethylisoxazol-4-yl)-2-arylthiazolidin-4-ones 3a-l have been synthesized from 4-amino-3,5-dimethylisoxazole 1 by condensation with aromatic aldehydes, followed by cyclization with mercaptoacetic acid in excellent yields, and have been evaluated for in vitro antioxidant activity. Based on potential antioxidant property, compounds 3c, 3e, 3h, 3i, and 3l have been screened for in vivo anti-inflammatory and analgesic activity. Molecular docking studies have also been carried out to balance the bioactivity results. From these results it is evident that the compound 3c shows potential anti-inflammatory and analgesic activity. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| 9 (RLIN) |
5009 |
| Topical term or geographic name entry element |
GENERAL CHEMISTRY |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| 9 (RLIN) |
15736 |
| Co-Author |
Kakkerla, Ramu |
| 773 0# - HOST ITEM ENTRY |
|---|
| Place, publisher, and date of publication |
New Delhi NISCAIR-CSIR 2005 |
| Title |
Indian journal of chemistry (Section B) |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
|---|
| URL |
http://nopr.niscair.res.in/bitstream/123456789/45702/1/IJCB%2058B%281%29%20109-119.pdf |
| Link text |
Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Koha item type |
Articles Abstract Database |
