| 000 -LEADER |
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| fixed length control field |
a |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20220208144436.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
220208b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
AIKTC-KRRC |
| Transcribing agency |
AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME |
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| 9 (RLIN) |
15946 |
| Author |
García-López, Elena Berenice |
| 245 ## - TITLE STATEMENT |
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| Title |
Evaluationofanti-inflammatoryactivityofmacroalgaecollectedfrombajacaliforniasur,Mexico |
| 250 ## - EDITION STATEMENT |
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| Volume, Issue number |
Vol.13(8) |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
M P |
| Name of publisher, distributor, etc. |
Innovare Academic Sciences Pvt Ltd |
| Year |
2021 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Pagination |
81-88p. |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc. |
Objective:This study aimed to establish the anti-inflammatory potential of macroalgae from Baja California Sur, Mexico. Methods: The anti-inflammatory activity of the extracts from 10 macroalgae species was evaluatedin vitro and in vivo. Dichloromethane, ethanolic, and aqueous extracts were obtained from each species. The criteria used to determine anti-inflammatory activity included 1) the membrane protection of human red blood cells (HRBCs) against hemolysis induced by hypotonicity, 2) the inhibition of heat-induced protein denaturation (IDP), and 3) the inhibition of mouse ear edema and the myeloperoxidase (MPO) enzyme.Results:The dichloromethane extracts of Gracilaria vermiculophyllaand Opuntiella californica were the most active, both in vitro and in vivo. Theseextracts resulted in values of HRBC membrane protection above 95%, which were similar to those obtained with diclofenac sodium. And reduce the inflammation with edema inhibition percentage up to 60 % while the control indomethacin was able to inhibit edema by 82.3 %. Conclusion:The bioprospection of several macroalgae species from Bahía de La Paz, Mexico, allowed the identification of two species withpromising anti-inflammatory activity. Gracilaria vermiculophyllashowed interesting topical anti-inflammatory effects and a profile of compounds(flavonoids and terpenes) that may contribute to the potential biological properties of this seaweed. This study represents the first report of the anti-inflammatory potential of O. californica. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| 9 (RLIN) |
4639 |
| Topical term or geographic name entry element |
PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| 9 (RLIN) |
15947 |
| Co-Author |
Muñoz-Ochoa, Mauricio |
| 773 0# - HOST ITEM ENTRY |
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| Title |
International journal of pharmacy and pharmaceutical science |
| Place, publisher, and date of publication |
M P Innovare Academic Sciences Pvt Ltd 2021 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| URL |
https://innovareacademics.in/journals/index.php/ijpps/article/view/41453/25193 |
| Link text |
Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
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| Koha item type |
Articles Abstract Database |
