MicroRNA-142-5p suppresses proliferation and invasion of non-small cell lung cancer cells by targeting programmed cell death receptor ligand 1 (Record no. 16934)

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control field 20220628101536.0
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040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
100 ## - MAIN ENTRY--PERSONAL NAME
9 (RLIN) 16864
Author Gao, Jing
245 ## - TITLE STATEMENT
Title MicroRNA-142-5p suppresses proliferation and invasion of non-small cell lung cancer cells by targeting programmed cell death receptor ligand 1
250 ## - EDITION STATEMENT
Volume, Issue number Vol.83(4), July-Aug
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mumbai
Name of publisher, distributor, etc. Indian Journal of Pharmaceutical Science
Year 2021
300 ## - PHYSICAL DESCRIPTION
Pagination 742-749p.
520 ## - SUMMARY, ETC.
Summary, etc. Lung cancer is one of the most deadly tumor disease in the world and most lung cancer is non-small cell
lung cancer. MicroRNAs are considered as a variety of endogenous non-coding RNA, acting as interference
during the process after transcription of gene. Recently, microRNA-142-5p, one of the microRNAs,
was reported to enhance anti-tumor immune response of non-small cell lung cancer cells by targeting
programmed cell death receptor ligand 1. Programmed cell death receptor ligand 1 was also believed to be
a regulator of cell proliferation and migration. However, the effect of microRNA-142-5p on proliferation
and invasion of non-small cell lung cancer cells via regulating programmed cell death receptor ligand 1
was still unknown. Thus, this study demonstrated that there was low expression level of microRNA-142-
5p in different non-small cell lung cancer cell lines. Programmed cell death receptor ligand 1 was proved
to be the target gene of microRNA-142-5p and microRNA-142-5p also had negative correlation with
programmed cell death receptor ligand 1. The high expression of microRNA-142-5p lead to suppression of
proliferation and invasion in non-small cell lung cancer cells by down regulation of programmed cell death
receptor ligand 1. The mechanism of microRNA-142-5p affecting proliferation and invasion of non-small
cell lung cancer cells via targeting programmed cell death receptor ligand 1 might give a new thought of
tumor therapy.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 4639
Topical term or geographic name entry element PHARMACEUTICS
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9 (RLIN) 15209
Co-Author Li, S.
773 0# - HOST ITEM ENTRY
Title Indian journal of pharmaceutical sciences
Place, publisher, and date of publication New Delhi
856 ## - ELECTRONIC LOCATION AND ACCESS
URL https://www.ijpsonline.com/articles/microrna1425p-suppresses-proliferation-and-invasion-of-nonsmall-cell-lung-cancer-cells-by-targeting-programmed-cell-deat.pdf
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          School of Pharmacy School of Pharmacy Archieval Section 2022-06-28 2022-0923 2022-06-28 2022-06-28 Articles Abstract Database
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