Therapeutic approaches of nanotechnology for epileptic seizures: a comprehensive review of current knowledge (Record no. 17318)
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| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220825100047.0 |
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| fixed length control field | 220825b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 17582 |
| Author | Shrivastava, Aman |
| 245 ## - TITLE STATEMENT | |
| Title | Therapeutic approaches of nanotechnology for epileptic seizures: a comprehensive review of current knowledge |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.56(3), Jul-Sep |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Karnataka |
| Name of publisher, distributor, etc. | Association of Pharmaceutical Teachers of India (APTI) |
| Year | 2022 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 628-635p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Epilepsy is a chronic neurological condition in which several neurotransmitters act like neuromodulators. The symptoms of epilepsy are caused by abnormal electrical discharges in a group of neurons in the hippocampus region of the brain. This can also affect electrical impulse generation, either in the focal area or in the hippocampus region of the brain. This review aimed to develop a better understanding of the transportation of nanoparticles across the blood-brain barrier and how to enhance the delivery of the drug in epileptic conditions by the utilization of nanomaterials. A few clinical studies have reported that antiepileptic drugs are generally used for the treatment of epilepsy by decreasing the frequency and intensity of seizures or preventing tissue damage in the brain. In long- term therapy, antiepileptic drugs are primarily administered via the oral route, but they are not always beneficial. Therefore, intravenous routes are especially used in serious epileptic conditions. In this review, we discussed the drug delivery study of antiepileptic drugs that are used in the form of nanoparticles that can easily be transported across the blood-brain barrier. Besides, the nanoparticles can easily cross the blood-brain barrier and increase the uptake into the target cells. Drug absorption into the brain is substantially limited by some factors, especially in the blood-brain barrier, which affects the potency of antiepileptic drugs to reach and remain inside the brain. Novel drug delivery systems have already been studied in many clinical trials to enhance the therapeutic efficacy of antiepileptic drugs in epileptic conditions. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 17583 |
| Co-Author | Gupta, Jeetendra K. |
| 773 0# - HOST ITEM ENTRY | |
| International Standard Serial Number | 0019-5464 |
| Title | Indian journal of pharmaceutical education and research |
| Place, publisher, and date of publication | Bengluru Association of Pharmaceutical Teachers of India (APTI) |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://ijper.org/sites/default/files/IndJPhaEdRes-56-3-628_0.pdf |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Permanent Location | Current Location | Shelving location | Date acquired | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| School of Pharmacy | School of Pharmacy | Archieval Section | 2022-08-25 | 2022-1362 | 2022-08-25 | 2022-08-25 | Articles Abstract Database |