Potential of ocimum sanctum to inhibit the growth of pseudomonas aeruginosa, a disease-causing micro-organism (Record no. 17344)

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control field 20220826145440.0
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040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
100 ## - MAIN ENTRY--PERSONAL NAME
9 (RLIN) 17626
Author Yadav, Raj Narayan
245 ## - TITLE STATEMENT
Title Potential of ocimum sanctum to inhibit the growth of pseudomonas aeruginosa, a disease-causing micro-organism
250 ## - EDITION STATEMENT
Volume, Issue number Vol.56(3) Jul-Sep
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Karnataka
Name of publisher, distributor, etc. Association of Pharmaceutical Teachers of India (APTI)
Year 2022
300 ## - PHYSICAL DESCRIPTION
Pagination 816-821p.
520 ## - SUMMARY, ETC.
Summary, etc. Aim and Objectives: Plants are a good source of secondary metabolites, which have huge
potential to kill micro-organisms. The present study aimed to evaluate the antimicrobial
activity of
Ocimum sanctum ethanol extract against drug-resistant and drug-sensitive
strains of
Pseudomonas aeruginosa (
P. aeruginosa). Materials and Methods: A total of
119 strains of
P. aeruginosa, 92 multidrug-resistant (MDR) and 27 pan sensitive strains
were included in the study, which were isolated from different human clinical samples.
Ocimum sanctum crude leaves extract was prepared with the standard “cold extraction
method”. The susceptibility agar dilution plates were made by mixing molten Mueller-
Hinton Agar (MHA) media with plant extract in different quantities to get the final extract
concentration of 0.2%, 0.1% and 0.05%. These plates were used for determining the
sensitive/ resistance nature of all strains of
P. aeruginosa against plant extract. Results:
Among 92 MDR strains in MHA plates with 0.05% of plant extract, 59 strains were
sensitive and 33 were resistant. The same MDR strains in MHA plate with 0.1% of the
extract showed somewhat similar trends, 61 sensitive and 31 resistant. Whereas with
0.2% of the extract, 67 strains were sensitive, 11 showed resistance while 14 showed
discrete colonies. Among 27 pan sensitive strains at 0.05% concentration, there was
complete growth inhibition in 23, while discrete colonies were observed in 4, though, at
0.1% and 0.2%, all strains were found as sensitive. Conclusion: Analysis of the present
study showed that
Ocimum sanctum extract possess compounds with antimicrobial
properties against commonly used isolates of
Pseudomonas aeruginosa strains.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 4639
Topical term or geographic name entry element PHARMACEUTICS
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 17627
Co-Author Kayesth, Sunil
773 0# - HOST ITEM ENTRY
Place, publisher, and date of publication Bengluru Association of Pharmaceutical Teachers of India (APTI)
International Standard Serial Number 0019-5464
Title Indian journal of pharmaceutical education and research
856 ## - ELECTRONIC LOCATION AND ACCESS
URL https://www.ijper.org/sites/default/files/IndJPhaEdRes-56-3-816.pdf
Link text Click here
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Koha item type Articles Abstract Database
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Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Permanent Location Current Location Shelving location Date acquired Barcode Date last seen Price effective from Koha item type
          School of Pharmacy School of Pharmacy Archieval Section 2022-08-26 2022-1394 2022-08-26 2022-08-26 Articles Abstract Database
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