Potential of ocimum sanctum to inhibit the growth of pseudomonas aeruginosa, a disease-causing micro-organism (Record no. 17344)
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control field | OSt |
005 - DATE AND TIME OF LATEST TRANSACTION | |
control field | 20220826145440.0 |
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fixed length control field | 220826b xxu||||| |||| 00| 0 eng d |
040 ## - CATALOGING SOURCE | |
Original cataloging agency | AIKTC-KRRC |
Transcribing agency | AIKTC-KRRC |
100 ## - MAIN ENTRY--PERSONAL NAME | |
9 (RLIN) | 17626 |
Author | Yadav, Raj Narayan |
245 ## - TITLE STATEMENT | |
Title | Potential of ocimum sanctum to inhibit the growth of pseudomonas aeruginosa, a disease-causing micro-organism |
250 ## - EDITION STATEMENT | |
Volume, Issue number | Vol.56(3) Jul-Sep |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Place of publication, distribution, etc. | Karnataka |
Name of publisher, distributor, etc. | Association of Pharmaceutical Teachers of India (APTI) |
Year | 2022 |
300 ## - PHYSICAL DESCRIPTION | |
Pagination | 816-821p. |
520 ## - SUMMARY, ETC. | |
Summary, etc. | Aim and Objectives: Plants are a good source of secondary metabolites, which have huge potential to kill micro-organisms. The present study aimed to evaluate the antimicrobial activity of Ocimum sanctum ethanol extract against drug-resistant and drug-sensitive strains of Pseudomonas aeruginosa ( P. aeruginosa). Materials and Methods: A total of 119 strains of P. aeruginosa, 92 multidrug-resistant (MDR) and 27 pan sensitive strains were included in the study, which were isolated from different human clinical samples. Ocimum sanctum crude leaves extract was prepared with the standard “cold extraction method”. The susceptibility agar dilution plates were made by mixing molten Mueller- Hinton Agar (MHA) media with plant extract in different quantities to get the final extract concentration of 0.2%, 0.1% and 0.05%. These plates were used for determining the sensitive/ resistance nature of all strains of P. aeruginosa against plant extract. Results: Among 92 MDR strains in MHA plates with 0.05% of plant extract, 59 strains were sensitive and 33 were resistant. The same MDR strains in MHA plate with 0.1% of the extract showed somewhat similar trends, 61 sensitive and 31 resistant. Whereas with 0.2% of the extract, 67 strains were sensitive, 11 showed resistance while 14 showed discrete colonies. Among 27 pan sensitive strains at 0.05% concentration, there was complete growth inhibition in 23, while discrete colonies were observed in 4, though, at 0.1% and 0.2%, all strains were found as sensitive. Conclusion: Analysis of the present study showed that Ocimum sanctum extract possess compounds with antimicrobial properties against commonly used isolates of Pseudomonas aeruginosa strains. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
9 (RLIN) | 4639 |
Topical term or geographic name entry element | PHARMACEUTICS |
700 ## - ADDED ENTRY--PERSONAL NAME | |
9 (RLIN) | 17627 |
Co-Author | Kayesth, Sunil |
773 0# - HOST ITEM ENTRY | |
Place, publisher, and date of publication | Bengluru Association of Pharmaceutical Teachers of India (APTI) |
International Standard Serial Number | 0019-5464 |
Title | Indian journal of pharmaceutical education and research |
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URL | https://www.ijper.org/sites/default/files/IndJPhaEdRes-56-3-816.pdf |
Link text | Click here |
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Source of classification or shelving scheme | |
Koha item type | Articles Abstract Database |
Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Permanent Location | Current Location | Shelving location | Date acquired | Barcode | Date last seen | Price effective from | Koha item type |
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School of Pharmacy | School of Pharmacy | Archieval Section | 2022-08-26 | 2022-1394 | 2022-08-26 | 2022-08-26 | Articles Abstract Database |