Protective effects of ficus benghalensis in streptozotocin (STZ) induced diabetic zebrafish (Danio rerio) model (Record no. 17345)
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| fixed length control field | a |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220826151727.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 220826b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 17628 |
| Author | Sabi, Essa M. |
| 245 ## - TITLE STATEMENT | |
| Title | Protective effects of ficus benghalensis in streptozotocin (STZ) induced diabetic zebrafish (Danio rerio) model |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.56(3), Jul-Sep |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Karnataka |
| Name of publisher, distributor, etc. | Association of Pharmaceutical Teachers of India (APTI) |
| Year | 2022 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 822-829p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Diabetes Mellitus (DM) is a chronic metabolic disorder that is characterized by hyperglycemia. Severe complications such as cardiovascular disease, neuropathy, nephropathy, and retinopathy are associated with DM. Objectives: To explore a safer treatment option with no/less adverse effects, we evaluated the potential of Ficus benghalensis to alleviate certain diabetic conditions. Materials and Methods: Administering streptozotocin to zebrafish intraperitoneally induced diabetes. After induction, Ficus benghalensis hydroethanolic bark extract was administered to zebrafish in different concentrations (5, 10, and 15 μg/mL). Biochemical blood parameters such as Blood Glucose, total cholesterol levels, triglycerides, and liver enzymes such as alkaline phosphatase, alanine aminotransferase, and aspartate aminotransferase were analyzed. Results: Treating the streptozotocin-induced group with Ficus benghalensis hydroethanolic bark had a hypoglycemic effect and reduced the cholesterol, triglycerides, and liver enzymes. The histopathological evaluation also showed improvement in the damaged pancreatic tissues. Conclusion: Our results suggest that Ficus benghalensis hydroethanolic bark extract can be used as a potent therapeutic candidate for treating diabetes. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 17629 |
| Co-Author | Mujamammi, Ahmed H. |
| 773 0# - HOST ITEM ENTRY | |
| International Standard Serial Number | 0019-5464 |
| Place, publisher, and date of publication | Bengluru Association of Pharmaceutical Teachers of India (APTI) |
| Title | Indian journal of pharmaceutical education and research |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://www.ijper.org/sites/default/files/IndJPhaEdRes-56-3-822.pdf |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Permanent Location | Current Location | Shelving location | Date acquired | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| School of Pharmacy | School of Pharmacy | Archieval Section | 2022-08-26 | 2022-1395 | 2022-08-26 | 2022-08-26 | Articles Abstract Database |