Anti-inflammatory effects of sargassum muticum ethanol extract in lipopolysaccharide-induced raw 264.7 cells and mouse ear edema models (Record no. 18380)
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| 000 -LEADER | |
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| fixed length control field | a |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20221202095358.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 221202b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 19297 |
| Author | Jeong, S. M. |
| 245 ## - TITLE STATEMENT | |
| Title | Anti-inflammatory effects of sargassum muticum ethanol extract in lipopolysaccharide-induced raw 264.7 cells and mouse ear edema models |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.84(1), Jan-Feb |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mumbai |
| Name of publisher, distributor, etc. | Indian Journal of Pharmaceutical Science |
| Year | 2022 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 230-238p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | This study investigated the effects and the anti-inflammatory activity of Sargassum muticum ethanol extract in lipopolysaccharide-induced RAW 264.7 murine macrophage cells and in a croton oil-induced mouse ear edema model. Pretreatment of lipopolysaccharide-induced RAW 264.7 cells with Sargassum muticum ethanol extract (0.1-100 μg/ml) inhibited lipopolysaccharide-induced production of nitric oxide, interleukin-6 and tumour necrosis factor alpha in a dose-dependent manner. The expression of lipopolysaccharide-induced, inducible nitric oxide synthase and cyclooxygenase-2 in the Sargassum muticum ethanol extract-treated group was also suppressed in a dose-dependent manner. Furthermore, we found that Sargassum muticum ethanol extract induced anti-inflammatory effects by inhibiting Mitogen- activated protein kinases (extracellular signal-regulated kinase, c-Jun N-terminal kinase and p38) and nuclear factor kappa B, p65 phosphorylation in lipopolysaccharide-stimulated RAW 264.7 cells. The anti- inflammatory activity of Sargassum muticum ethanol extract in vivo was evaluated in the ear edema model of a croton oil-treated mouse. Compared to the untreated control, croton oil-induced ear edema was found to be reduced by about 33 % upon treatment with 250 mg/kg Sargassum muticum ethanol extract. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 7047 |
| Co-Author | Kim, M. J. |
| 773 0# - HOST ITEM ENTRY | |
| Title | Indian journal of pharmaceutical sciences |
| Place, publisher, and date of publication | New Delhi Indian Pharmaceutical Association |
| International Standard Serial Number | 0250-474X |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://www.ijpsonline.com/articles/antiinflammatory-effects-of-emsargassum-muticumem-ethanol-extract-in-lipopolysaccharideinduced-raw-2647-cells-and-mouse-.pdf |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Permanent Location | Current Location | Shelving location | Date acquired | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| School of Pharmacy | School of Pharmacy | Archieval Section | 2022-12-02 | 2022-2259 | 2022-12-02 | 2022-12-02 | Articles Abstract Database |