Alpha-amylase inhibitory and antioxidant activities in aqueous acetone extract and its fractions from ampelocissus martini root (Record no. 19427)
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| fixed length control field | a |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20230524094944.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 230524b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 20939 |
| Author | Siripipatthana, Patthraporn |
| 245 ## - TITLE STATEMENT | |
| Title | Alpha-amylase inhibitory and antioxidant activities in aqueous acetone extract and its fractions from ampelocissus martini root |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol84(4), Jul-Aug |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mumbai |
| Name of publisher, distributor, etc. | Indian Journal of Pharmaceutical Science |
| Year | 2022 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 929-937p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | This study aimed to evaluate and correlate phytochemical content, antioxidant activity and alpha-amylase inhibitory activity in aqueous acetone extract and fractions derived from it (ethyl acetate fraction, water- soluble fraction, aqueous methanol fraction and aqueous acetone fraction) which are obtained from Ampelocissus martini Planch. root. Ethyl acetate fraction and aqueous acetone fraction had the highest total phenolic content and total proanthocyanidin content, respectively. 2,2-diphenyl-1-picrylhydrazyl, 2,2'-azino-bis (3-ethylbenzthiazoline-6-sulphonic acid), cupric reducing antioxidant capacity and ferric reducing antioxidant power assays showed that aqueous acetone fraction had higher antioxidant activity compared to other samples and standards. Acarbose and all samples except aqueous methanol fraction inhibited alpha-amylase, a key enzyme linked to type 2 diabetes, in a dose-dependent manner and aqueous acetone fraction showed the strongest inhibition (half-maximal inhibitory concentration=8.77±0.28 μg/ ml). Aqueous acetone fraction was a mixed noncompetitive inhibitor of the enzyme. Correlation analysis showed strong positive correlations among proanthocyanidin content, antioxidant activity and alpha- amylase inhibitory activity. These results suggest that aqueous acetone fraction, proanthocyanidins-rich fraction from Ampelocissus martini root, may be used for effective diabetes management because of its high potential antioxidant activity and alpha-amylase inhibitory activity. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 773 0# - HOST ITEM ENTRY | |
| International Standard Serial Number | 0250-474X |
| Place, publisher, and date of publication | New Delhi Indian Pharmaceutical Association |
| Title | Indian journal of pharmaceutical sciences |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://www.ijpsonline.com/articles/alphaamylase-inhibitory-and-antioxidant-activities-in-aqueous-acetone-extract-and-its-fractions-from-emampelocissus-mart.pdf |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Permanent Location | Current Location | Shelving location | Date acquired | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| School of Pharmacy | School of Pharmacy | Archieval Section | 2023-05-24 | 2023-0849 | 2023-05-24 | 2023-05-24 | Articles Abstract Database |