Antinociceptive and anti-inflammatory activity of extract of acorus calamus rhizomes in experimental animal models (Record no. 20663)
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| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240223112527.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 240223b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 22892 |
| Author | Datchanamurthy, Barathane |
| 245 ## - TITLE STATEMENT | |
| Title | Antinociceptive and anti-inflammatory activity of extract of acorus calamus rhizomes in experimental animal models |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.17(3), Jul-Sep |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | M P |
| Name of publisher, distributor, etc. | BRNSS Publication Hub. |
| Year | 2023 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 226-232p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Background: Complex biological responses like inflammation are part and parcel of body’s immune system to any noxious stimuli. Mediators released during inflammation irritate the free nerve endings which are perceived by the body as pain. Hence, inflammation and pain often coexist and add up significant morbidity in humans. Aims and Objectives: The aims and objectives of the study are to evaluate the antinociceptive and anti-inflammatory activity of extract of Acorus calamus rhizomes in experimental animal models. Materials and Methods: Ethanolic extract of A. calamus rhizomes was prepared by Soxhlet extraction. Inflammation, both acute and chronic, was tested using carrageenan-induced paw edema and cotton pellet-induced granuloma model in rats whereas peripheral and central anti-nociceptive activity was tested using acetic acid-induced writhing in mice and tail immersion test in rats. Results: Significant reduction in writhing, paw edema volume, granuloma size, and increase in reaction time with tail immersion was observed with the extract treated groups in a dose-dependent manner. standard drug diclofenac was found to be better than the extract but failed to show significant difference with a higher dose of the extract. Conclusion: The ethanolic extract of A. calamus rhizome possesses significant antinociceptive and anti-inflammatory activity. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 773 0# - HOST ITEM ENTRY | |
| Title | International journal of green pharmacy |
| International Standard Serial Number | 0973-8258 |
| Place, publisher, and date of publication | Mandsaur B.R. Nahata Smriti Sansthan |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://www.greenpharmacy.info/index.php/ijgp/article/view/3473 |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Permanent Location | Current Location | Shelving location | Date acquired | Barcode | Date last seen | Price effective from | Koha item type |
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| School of Pharmacy | School of Pharmacy | Archieval Section | 2024-02-23 | 2024-0184 | 2024-02-23 | 2024-02-23 | Articles Abstract Database |