Review on novel approach of oral drug administration (Record no. 20838)

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040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
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9 (RLIN) 23158
Author Vaithilingam, V.
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Title Review on novel approach of oral drug administration
Remainder of title : gastro retentive drug delivery system
250 ## - EDITION STATEMENT
Volume, Issue number Vol.85(4), Jul-Aug
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Mumbai
Name of publisher, distributor, etc. Indian Journal of Pharmaceutical Science
Year 2023
300 ## - PHYSICAL DESCRIPTION
Pagination 853-862p.
520 ## - SUMMARY, ETC.
Summary, etc. Over several centuries, oral dosage forms have remained incomparably superior to alternative medication
delivery methods. For its ease of formulation and administration, its stability, and its excellent rate of patient
compliance, the oral route is preferred. Gastric emptying has been a major drawback for drugs that stay for
a very short period in the stomach. An innovative method of gastro-intestinal retention allows the dosage
form to stay in the gastrointestinal region for a longer period and maximize drug release. Gastro retentive
drug delivery system is applied for enhancing bioavailability, local action in the gastric region, maintaining
steady drug concentrations and minimising the dosage regimen. This review discusses the approaches used
in gastro retentive drug delivery system, which include floating, high density, muco-adhesive, magnetic and
various other systems. Floating systems are the most widely used approach under gastro retentive drug
delivery system. These are extensively used because of their simplicity. Drug content, hardness, particle size
analysis, weight variation and friability are some of the conventional tests for any dosage form. Along with
these, buoyancy studies, dissolution studies, and swelling index are also carried out. Techniques like magnetic
resonance imaging are widely used in in vivo evaluation. Yet, evaluating entire in vivo efficacy in the case of
small animals is a significant drawback. Gastro retentive drug delivery system is regarded as a formulative
strategy to improve the activity and bioavailability of the active pharmaceutical ingredient based on its
benefits and applications. It is anticipated that numerous more studies will uncover Gastro retentive drug
delivery system's full potential.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 4639
Topical term or geographic name entry element PHARMACEUTICS
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9 (RLIN) 23159
Co-Author Dhamotharaswamy, Kumudha
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Title Indian journal of pharmaceutical sciences
International Standard Serial Number 0250-474X
Place, publisher, and date of publication New Delhi Indian Pharmaceutical Association
856 ## - ELECTRONIC LOCATION AND ACCESS
URL https://www.ijpsonline.com/articles/a-review-on-novel-approach-of-oral-drug-administration-gastro-retentive-drug-delivery-system.pdf
Link text Click here
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Source of classification or shelving scheme
Koha item type Articles Abstract Database
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          School of Pharmacy School of Pharmacy Archieval Section 2024-04-04 2024-0396 2024-04-04 2024-04-04 Articles Abstract Database
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