Walnut green husk extract suppresses ovarian cancer cell proliferation, migration and invasion via modulating microRNA-144-3p (Record no. 20849)
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| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240406110422.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 240406b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | AIKTC-KRRC |
| Transcribing agency | AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 23177 |
| Author | Yanan Liu, Lin Yang |
| 245 ## - TITLE STATEMENT | |
| Title | Walnut green husk extract suppresses ovarian cancer cell proliferation, migration and invasion via modulating microRNA-144-3p |
| 250 ## - EDITION STATEMENT | |
| Volume, Issue number | Vol.85(4), Jul-Aug |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Mumbai |
| Name of publisher, distributor, etc. | Indian Journal of Pharmaceutical Science |
| Year | 2023 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Pagination | 972-978p. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Previous reports have indicated that walnut green husk extract has an inhibitory effect on human cancer development. This project aimed to explore the influence of walnut green husk extract on ovarian cancer. SKOV3 cells were exposed to various doses of walnut green husk extract or transfected with microRNA- control or microRNA-144-3p. Meanwhile, anti-microRNA-144-3p or anti-microRNA-control-transfected SKOV3 cells were treated with high-dose walnut green husk extract. Cell counting kit-8, flow cytometry and Transwell monitored cell activity, cycle progression, migration and invasion. Cyclin D1, matrix metallopeptidase 2, matrix metallopeptidase 9, microRNA-144-3p contents were appraised via Western blot or real-time quantitative polymerase chine reaction. After treatment with different concentrations of walnut green husk extract, cell activity, cycle progression, migration, invasion and cyclin D1, matrix metallopeptidase 2 and matrix metallopeptidase 9 protein expression were decreased and microRNA-144-3p level increased in a dose-dependent manner. MicroRNA-144-3p upregulation might hinder cell activity, cycle progression, migration and invasion. Additionally, miR-144-3p knockdown might abolish the repression of high-dose walnut green husk extract on Janus kinase 2 and signal transducer, and activator of transcription 3 expression. Walnut green husk extract might block ovarian cancer development via modulating the microRNA-144-3p/ Janus kinase 2/signal transducer and activator of transcription 3 pathway. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| 9 (RLIN) | 4639 |
| Topical term or geographic name entry element | PHARMACEUTICS |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| 9 (RLIN) | 23178 |
| Co-Author | Gu, Y. |
| 773 0# - HOST ITEM ENTRY | |
| International Standard Serial Number | 0250-474X |
| Place, publisher, and date of publication | New Delhi Indian Pharmaceutical Association |
| Title | Indian journal of pharmaceutical sciences |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| URL | https://www.ijpsonline.com/articles/walnut-green-husk-extract-suppresses-ovarian-cancer-cell-proliferation-migration-and-invasion-emviaem-modulating-microrn.pdf |
| Link text | Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | |
| Koha item type | Articles Abstract Database |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Permanent Location | Current Location | Shelving location | Date acquired | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| School of Pharmacy | School of Pharmacy | Archieval Section | 2024-04-06 | 2024-0407 | 2024-04-06 | 2024-04-06 | Articles Abstract Database |