| 000 -LEADER |
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a |
| 003 - CONTROL NUMBER IDENTIFIER |
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OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20250109161851.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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250109b xxu||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
AIKTC-KRRC |
| Transcribing agency |
AIKTC-KRRC |
| 100 ## - MAIN ENTRY--PERSONAL NAME |
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| 9 (RLIN) |
25057 |
| Author |
Patil, Jayesh D. |
| 245 ## - TITLE STATEMENT |
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| Title |
Development and validation of RP-HPLC and UV spectroscopy method for the determination of diroximel fumarate in bulk drug and pharmaceutical dosage form |
| 250 ## - EDITION STATEMENT |
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| Volume, Issue number |
Vol.14(3), Jul-Sep |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Place of publication, distribution, etc. |
Raipur |
| Name of publisher, distributor, etc. |
Asian Pharma Press |
| Year |
2024 |
| 300 ## - PHYSICAL DESCRIPTION |
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| Pagination |
147-150p. |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc. |
Two new, simple, specific, precise and accurate UV-spectrophotometric and one reverse phase high performance liquid chromatography methods have been developed for the estimation of Diroximel Fumarate in Pharmaceutical dosage form. First UV-spectrophotometric methods show absorption maxima at 253nm for the Diroximel Fumarate. Percentage mean recovery obtained was 100.00%; coefficient of variance was found to be less than 2% and linearity coefficient was 0.9998. Linear response obtained for Diroximel Fumarate was in the concentration range of 0.5-2.5?g/ml. The limit of detection and limit of quantification for Diroximel was found to be 0.049?g/ml and 0.149?g/ml, respectively, and Second RP-HPLC method, chromatography analysis is carried out using Methanol: 10mm of KH2PO4 buffer solution (pH 3.1) (70:30%, v/v) as the mobile phase and C18 Waters (4.6mm x 150mm), 5.0µ column as stationery phase with detection wavelength of 272nm linearity was obtained in the concentration range of 5-25µg/ml for Diroximel Fumarate. Both UV-spectrophotometric and reverse phase high performance liquid chromatography methods were statistically validated according to I.C.H. Guidelines. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| 9 (RLIN) |
4642 |
| Topical term or geographic name entry element |
Humanities and Applied Sciences |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| 9 (RLIN) |
24937 |
| Co-Author |
Dhankani, Amitkumar R. |
| 773 0# - HOST ITEM ENTRY |
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| Title |
Asian journal of pharmaceutical analysis |
| Place, publisher, and date of publication |
Raipur A & V Publications |
| International Standard Serial Number |
2231-5667 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| URL |
https://ajpaonline.com/AbstractView.aspx?PID=2024-14-3-7 |
| Link text |
Click here |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
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| Koha item type |
Articles Abstract Database |
