Proximate composition, ionomics, phytochemical, antioxidant, anti-diabetic and acetylcholinesterase inhibitory activity of cucumis species from western ghats of India
By: Attar, U. A
.
Contributor(s): Ghane, S. G.
Publisher: Mumbai Indian Journal of Pharmaceutical Science 2021Edition: Vol.83(4), July-Aug.Description: 679-694p.Subject(s): PHARMACEUTICSOnline resources: Click here
In:
Indian journal of pharmaceutical sciencesSummary: The present study was intended to evaluate nutrition and antioxidant potential of four Cucumis species
from the Western Ghats of India. All the studied Cucumis species were found to be an excellent source
of nutraceuticals. Leaves and fruits of Cucumis indicus were rich source of energy (296.84±0.20 and
333.52±0.15 kcal/100 g respectively) and several minerals. Cucumis maderaspatanus exhibited the highest
flavonoids, tannins and terpenoids along with highest antioxidant potential. Chemometric analysis
highlighted the influence of phytochemicals on the antioxidant activities from the organic and aqueous
solvents extracts of four Cucumis species, wherein organic extracts found superior. Ethanolic leaf and fruit
extracts of Cucumis maderaspatanus demonstrated highest alpha-amylase inhibitory activity (58.58±0.63
and 45.43±0.27 % at 1 mg extract). Similar trend was observed for alpha-glucosidase inhibition from the
fruit extract of maderaspatanus (74.31±3.75 % at 100 μg extract). Acetone fruit extract of Cucumis indicus
revealed the highest acetylcholinesterase inhibitory activity (31.63±0.16 % at 100 μg extract). Further,
extensive research work is needed to explore the Cucumis species as functional food to manage diabetes
mellitus and Alzheimer’s diseases.
| Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
|---|---|---|---|---|---|---|
Articles Abstract Database
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School of Pharmacy Archieval Section | Not for loan | 2022-0917 |
The present study was intended to evaluate nutrition and antioxidant potential of four Cucumis species
from the Western Ghats of India. All the studied Cucumis species were found to be an excellent source
of nutraceuticals. Leaves and fruits of Cucumis indicus were rich source of energy (296.84±0.20 and
333.52±0.15 kcal/100 g respectively) and several minerals. Cucumis maderaspatanus exhibited the highest
flavonoids, tannins and terpenoids along with highest antioxidant potential. Chemometric analysis
highlighted the influence of phytochemicals on the antioxidant activities from the organic and aqueous
solvents extracts of four Cucumis species, wherein organic extracts found superior. Ethanolic leaf and fruit
extracts of Cucumis maderaspatanus demonstrated highest alpha-amylase inhibitory activity (58.58±0.63
and 45.43±0.27 % at 1 mg extract). Similar trend was observed for alpha-glucosidase inhibition from the
fruit extract of maderaspatanus (74.31±3.75 % at 100 μg extract). Acetone fruit extract of Cucumis indicus
revealed the highest acetylcholinesterase inhibitory activity (31.63±0.16 % at 100 μg extract). Further,
extensive research work is needed to explore the Cucumis species as functional food to manage diabetes
mellitus and Alzheimer’s diseases.
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