Synthesis of transition metal complexes of isoniazid derivatives and urease inhibition activity detection (Record no. 17377)

000 -LEADER
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003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20220901104901.0
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fixed length control field 220901b xxu||||| |||| 00| 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency AIKTC-KRRC
Transcribing agency AIKTC-KRRC
100 ## - MAIN ENTRY--PERSONAL NAME
9 (RLIN) 17685
Author Zhang, Yi-Heng
245 ## - TITLE STATEMENT
Title Synthesis of transition metal complexes of isoniazid derivatives and urease inhibition activity detection
250 ## - EDITION STATEMENT
Volume, Issue number Vol.56(2), Apr-June
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Karnataka
Name of publisher, distributor, etc. Association of Pharmaceutical Teachers of India (APTI)
Year 2022
300 ## - PHYSICAL DESCRIPTION
Pagination 573-579p.
520 ## - SUMMARY, ETC.
Summary, etc. It have been reported that the transition metal complex of Schiff base ligands have the
ability to inhibit urease. Herein, in this manuscript, two novel transition metal complexes
[Cd2
(L)2·(H 2
O)] (1), [Pb(L)·, [Pbe2
) were synthesized based on chelating hydrazone
ligand
N‘-(pyridin-2-ylmethylene)isonicotinohydrazide (L). These compounds were tested
by single crystal X-ray diffraction and determined by structure and tested for urease
resistance
in vitro. The complex 2 exhibited better the activities of inhibiting than the
positive control acetohydroxamic acid with an IC50 =2.5
μM, while the complex 1
showed weak activity, and complex 2 acted as an effective urease inhibitor.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
9 (RLIN) 4639
Topical term or geographic name entry element PHARMACEUTICS
700 ## - ADDED ENTRY--PERSONAL NAME
9 (RLIN) 17686
Co-Author Fang, Ze-Yu
773 0# - HOST ITEM ENTRY
Title Indian journal of pharmaceutical education and research
International Standard Serial Number 0019-5464
Place, publisher, and date of publication Bengluru Association of Pharmaceutical Teachers of India (APTI)
856 ## - ELECTRONIC LOCATION AND ACCESS
URL https://www.ijper.org/sites/default/files/IndJPhaEdRes-56-2-573.pdf
Link text Click here
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Koha item type Articles Abstract Database
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Permanent Location Current Location Shelving location Date acquired Barcode Date last seen Price effective from Koha item type
          School of Pharmacy School of Pharmacy Archieval Section 2022-09-01 2022-1450 2022-09-01 2022-09-01 Articles Abstract Database
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