Synthesis of transition metal complexes of isoniazid derivatives and urease inhibition activity detection (Record no. 17377)
[ view plain ]
000 -LEADER | |
---|---|
fixed length control field | a |
003 - CONTROL NUMBER IDENTIFIER | |
control field | OSt |
005 - DATE AND TIME OF LATEST TRANSACTION | |
control field | 20220901104901.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
fixed length control field | 220901b xxu||||| |||| 00| 0 eng d |
040 ## - CATALOGING SOURCE | |
Original cataloging agency | AIKTC-KRRC |
Transcribing agency | AIKTC-KRRC |
100 ## - MAIN ENTRY--PERSONAL NAME | |
9 (RLIN) | 17685 |
Author | Zhang, Yi-Heng |
245 ## - TITLE STATEMENT | |
Title | Synthesis of transition metal complexes of isoniazid derivatives and urease inhibition activity detection |
250 ## - EDITION STATEMENT | |
Volume, Issue number | Vol.56(2), Apr-June |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Place of publication, distribution, etc. | Karnataka |
Name of publisher, distributor, etc. | Association of Pharmaceutical Teachers of India (APTI) |
Year | 2022 |
300 ## - PHYSICAL DESCRIPTION | |
Pagination | 573-579p. |
520 ## - SUMMARY, ETC. | |
Summary, etc. | It have been reported that the transition metal complex of Schiff base ligands have the ability to inhibit urease. Herein, in this manuscript, two novel transition metal complexes [Cd2 (L)2·(H 2 O)] (1), [Pb(L)·, [Pbe2 ) were synthesized based on chelating hydrazone ligand N‘-(pyridin-2-ylmethylene)isonicotinohydrazide (L). These compounds were tested by single crystal X-ray diffraction and determined by structure and tested for urease resistance in vitro. The complex 2 exhibited better the activities of inhibiting than the positive control acetohydroxamic acid with an IC50 =2.5 μM, while the complex 1 showed weak activity, and complex 2 acted as an effective urease inhibitor. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
9 (RLIN) | 4639 |
Topical term or geographic name entry element | PHARMACEUTICS |
700 ## - ADDED ENTRY--PERSONAL NAME | |
9 (RLIN) | 17686 |
Co-Author | Fang, Ze-Yu |
773 0# - HOST ITEM ENTRY | |
Title | Indian journal of pharmaceutical education and research |
International Standard Serial Number | 0019-5464 |
Place, publisher, and date of publication | Bengluru Association of Pharmaceutical Teachers of India (APTI) |
856 ## - ELECTRONIC LOCATION AND ACCESS | |
URL | https://www.ijper.org/sites/default/files/IndJPhaEdRes-56-2-573.pdf |
Link text | Click here |
942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
Source of classification or shelving scheme | |
Koha item type | Articles Abstract Database |
Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Permanent Location | Current Location | Shelving location | Date acquired | Barcode | Date last seen | Price effective from | Koha item type |
---|---|---|---|---|---|---|---|---|---|---|---|---|
School of Pharmacy | School of Pharmacy | Archieval Section | 2022-09-01 | 2022-1450 | 2022-09-01 | 2022-09-01 | Articles Abstract Database |